Stem cell biology and clonal expansion in normal and adenomatous human intestinal crypts
Gastrointestinal cancer is thought to be primarily a disease of stem cells, whereby a tumorigenic stem cell clone can expand within an individual colonic crypt and then within the epithelium to form an adenoma - the pre-malignant lesion of the colon. However, data demonstrating stem cell populations...
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University College London (University of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602832 |