Relevance of pro-angiogenic signalling as a mode of relapse to anti-androgen therapy in prostate cancer
Administration of bicalutamide to LNCaP tumours induces a rapid and sustained hypoxia in the prostate. This treatment-induced hypoxia (> 14 days) promotes an increased synthesis of the CXC-chemokine Interleukin-8(CXCL8) co-incident with increasing oxygen tension and the restoration of tumour vasc...
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Queen's University Belfast
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602503 |