Inclusion formation in Huntington's disease models

Huntington's disease (HD) is a progressive genetic neurodegenerative disease caused by the expansion of the CAG repeat in the <i>HD </i>gene and by the expression of pathological polyglutamine tracts in the huntingtin protein. Abnormal aggregates of protein (known as neuronal intran...

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Bibliographic Details
Main Author: Gong, B.
Published: University of Cambridge 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599486