The role of complexin II in the synaptic function of the hippocampus in neurologically normal and transgenic Huntington's disease mice

Complexin II protein expression is progressively reduced in brain tissue from Huntington’s disease (HD) patients and from the R6/2 mouse model of HD. Mice lacking complexin II (<i>Cplx2</i><sup>-/-</sup>mice) show specific cognitive deficits that reflect those seen in R6/2 mi...

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Bibliographic Details
Main Author: Gibson, H. E.
Published: University of Cambridge 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599395