The role of phosphoinositide 3-kinases in neutrophil chemotaxis

There are four class I phosphoinositide 3-kine4ase (PI3K) isoforms (α, β, γ and δ) which are responsible for the production of the signalling molecule PtdIns(3,4,5)P<sub>3</sub> at the plasma membrane. Class I PI3Ks have been shown to be required for neutrophil chemotaxis, however their...

Full description

Bibliographic Details
Main Author: Ferguson, G. J.
Published: University of Cambridge 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598984