Genetic and biochemical studies of the biosynthesis of glycopeptide and aminoglycoside antibiotics

My project explored the biosynthesis of teicoplanin and neomycin as representatives of glycopeptides and aminoglycosides respectively, with a focus on the characterisation of the biosynthetic enzymes and the development of methods for targeted gene disruption in the producer strains. Both <i>A...

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Bibliographic Details
Main Author: Fan, Q.
Published: University of Cambridge 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598931