Dynamics, stability and formation of amyloid fibrils : insights from mass spectrometry

In this thesis I have used electrospray mass spectrometry (ESI-MS) to investigate various aspects of amyloid fibrils, including their mechanism of formation, their structure and dynamics, and approaches to inhibit fibril development. I have used hydrogen exchange methods coupled with ESI-MS to exami...

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Bibliographic Details
Main Author: Caddy, G. L.
Published: University of Cambridge 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597207