The functional characterisation of Ku in the budding yeast, Saccharomyces cerevisiae

A major component of the predominant DSB repair pathway in mammalian cells is the DNA-dependent protein kinase (DNA-PK) which consists of a catalytic subunit, DNA-PKcs, and a DNA binding component, Ku (A heterodimer of 70 and 80kDa polypeptides). The identification of a putative Ku70 homologue in th...

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Bibliographic Details
Main Author: Boulton, S. J.
Published: University of Cambridge 1998
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596802