FBXW7 (hCDC4) E3-ubiquitin ligase receptor : lineage potential and its commitment to cancer

The crucial decision between stem cell self-renewal and differentiation must be tightly controlled, as it could otherwise contribute to tumorigenesis from expanding number of immortal, proliferative, partially differentiated cells. Despite the well-established links between signalling and transcript...

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Bibliographic Details
Main Author: Li, Ningning
Published: University of Nottingham 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.595677