The role of the hexosamine biosynthesis pathway in control of hepatic glucose metabolism
Type 2 diabetes is associated with increased hepatic lipogenesis and glucose production. Enzymes of lipogenesis are co-ordinately induced by insulin and glucose. However, the enzyme glucose 6-phosphatase (G6Pc), which catalyses the final reaction in hepatic glucose production is repressed by insulin...
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University of Newcastle upon Tyne
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594562 |