Solution structure of the factor VIII binding region on von Willebrand factor

The preservation of haemostatic integrity is secured by the activities of von Willebrand factor (VWF). Upon vascular damage, VWF acts as a molecular bridge facilitating the initial adhesion and aggregation of platelets to the site of vessel injury, and consequently thrombus formation ensues. Further...

Full description

Bibliographic Details
Main Author: Shiltagh, N.
Published: University College London (University of London) 2013
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594379