Study of cyclophilin A function in models of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease targeting preferentially motor neurons. Cyclophilin A (CypA) was identified as a hallmark of disease in mutant SODl (mSOD1) animal models of familial ALS (fAlS) at a presymptomatic stage, and in sporadic (sALS) patients (M...

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Bibliographic Details
Main Author: Lauranzano, Eliana
Published: Open University 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594093