The regulation of p53-dependent microRNA expression in response to genotoxic stress

Introduction: miR-16 and miR-26a have been identified as key effectors of the p53 pathway in response to genotoxic stress. This work is focused on preliminary elucidation of regulatory mechanisms by which p53 controls expression of miR-16 and miR-26a and characterisation of their gene targets involv...

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Bibliographic Details
Main Author: Purmessur, Nadia Sheree
Other Authors: Barlev, Nickolai
Published: University of Leicester 2014
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593771