Species differences in the induction of cytochrome P4503A

Species differences in the induction mechanisms of CYP3A isoenzymes were investigated in this project using several structurally different drugs in rat, dog or human <I>in vitro </I>and <I>in vivo </I>models. Induction of CYP3A was assessed by observing the levels of CYP3A ac...

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Bibliographic Details
Main Author: Jackson, F. C.
Published: University of Aberdeen 1998
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.592621