Regulation of M-type K+ channels by competing G protein coupled receptor signalling pathways
KCNQ (Kv7, M-type) K+ channels are key regulators of neuronal excitability. KCNQ channels are modulated by specific G protein coupled receptors which inhibit the channel via (1) a depletion in membrane phosphatidylinositol 4,5-bisphosphate (P1P2) or (2) via Ca2+-calrnodulin (CaM). Despite the sugges...
| Main Author: | |
|---|---|
| Published: |
University of Leeds
2012
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590312 |