Determining the role of N-cadherin in the formation of the myeloma niche

Introduction: Multiple myeloma is a plasma cell malignancy that causes extensive osteolytic bone disease. Present treatments target end stage disease but understanding how bone lesions are initiated may offer new approaches to prevent/suppress colonization. It is clear that myeloma cells form specif...

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Bibliographic Details
Main Author: Al-Amer, Osama Mohammed
Other Authors: Eaton, Colby
Published: University of Sheffield 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589441