Formulation of novel cross-linked sterically stabilised polyplexes with polyethylene glycol for DNA delivery
Linear poly(amidoamine) (PAA) cationic polymers complexed with DNA have potential as non-viral nucleic acid delivery systems. However, they have poor in vivo biodistribution and a tendency to aggregate. PEGylation polymers are a potential solution for these problems but previous work shows that they...
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University of Nottingham
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588065 |