Development of methods to predict and enhance the physical stability of hot melt extruded solid dispersions

The application of amorphous solid dispersions is one of the most widely used formulation strategies for the enhancement of in-vitro and in-vivo performance of poorly water-soluble drugs. However, because of their meta-stable nature, the physical stability of amorphous solid dispersions has been con...

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Bibliographic Details
Main Author: Yang, Ziyi
Published: University of East Anglia 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.585561