Genetic, epigenetic and functional analysis of tumorigenesis in neurofibromatosis type 1 (NF1)
Neurofibromatosis Type 1 (NF1) is an autosomal dominant disorder caused by constitutional inactivation of the NF1 gene. NF1 is associated with extreme phenotypic variability and results in an increased risk of developing benign and malignant peripheral nerve sheath tumours (MPNSTs). The molecular me...
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Cardiff University
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.585164 |