Bioresponsive polymer therapeutics containing coiled-coil motifs
Polyethyleneglycol (PEG) conjugates of peptides, proteins and an aptamer are in routine clinical use as first generation nanomedicines. Here a new family of polymer therapeutics based on PEG conjugates containing a coiled-coil peptide motif as a molecular switch are proposed. The coiled-coil motif i...
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Cardiff University
2009
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584694 |