Bioresponsive polymer therapeutics containing coiled-coil motifs

Polyethyleneglycol (PEG) conjugates of peptides, proteins and an aptamer are in routine clinical use as first generation nanomedicines. Here a new family of polymer therapeutics based on PEG conjugates containing a coiled-coil peptide motif as a molecular switch are proposed. The coiled-coil motif i...

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Bibliographic Details
Main Author: Deacon, Samuel Philip Edward
Published: Cardiff University 2009
Subjects:
615
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584694