Regulation of interleukin-18 signalling in dendritic cells

This study demonstrates the mechanism of regulation of IL-18 function by the pro- and anti-inflammatory cytokines, TNFalpha and TGFbeta respectively. The importance of the antagonistic interaction between these two cytokines, to control IL-18 signalling, has been demonstrated using an in vitro model...

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Bibliographic Details
Main Author: Koutoulaki, Anna
Published: Cardiff University 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584504