Liver-X-receptor-mediated expression of key genes in macrophages implicated in the control of cholesterol homeostasis and atherosclerosis
Atherosclerosis is a leading cause of morbidity and mortality in the western world. The deposition of lipoprotein cholesterol in the arterial wall is a critical early step in the pathogenesis of atherosclerosis. These atherogenic lipoproteins are then taken up by macrophages to transform into lipid-...
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Cardiff University
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584316 |