Design and synthesis of Combretastatin A-4 like chalcones and their analogues, and other anticancer agents

This thesis covers work investigating the design, synthesis and evaluation of Combretastatin A-4 like chalcones and their analogues, and other anticancer agents. The first two chapters are an introduction to cancer chemotherapy and the development of tubulin as a target for chemotherapy. Chapter one...

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Bibliographic Details
Main Author: Armitage, Edward Simon Marco
Published: Cardiff University 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584250