Design, synthesis and biological evaluation of some novel nucleotide prodrugs as potential anticancer agents

The development of phosphoramidates as a new pronucleotide approach has shown to lead to a significant boost in activity for a series of antiviral nucleoside analogues. Given the importance of nucleoside analogues in anticancer therapy and the need of more potent drugs against what is considered the...

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Bibliographic Details
Main Author: Congiatu, Costantino
Published: Cardiff University 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583877