Development of a synthetic uPAR targeted gene delivery system
Preliminary flow cytometry experiments studied the ability of the peptides, CLNGGTC (u7) and GVSNKYFSNIHWG (Gu11G), derived from the binding region of uPA to inhibit uPA-FITC binding to U937 cells. The optimised trimethylated chitosan oligomer (TMO) was functionalised with chloroacetic acid to give...
Main Author: | |
---|---|
Published: |
Cardiff University
2006
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583842 |