A-aryl quaternary centres via asymmetric vicarious nucleophilic substitution

This dissertation first describes a new method for the formation of a-aryl lactams based on the Vicarious Nucleophilic Substitution reaction. The route involves the three-component coupling of a nitroarene, an a-phenylsulfanyl lactam and an electrophile. The process incorporates various electrophile...

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Bibliographic Details
Main Author: Davies, Christopher Alan
Published: Cardiff University 2005
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583540