New routes to 2,5-disubstituted tetrahydropyrans and P-stereogenic heterocycles via ring-closing metathesis

New methodologies have been developed for the synthesis of 2,5-disubstituted tetrahydropyrans and for the asymmetric synthesis of P-stereogenic phospholene boranes. Synthesis of 2,5-disubstituted tetrahydropyrans in a racemic fashion was achieved via Grignard addition, O-alkylation, ring-closing met...

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Bibliographic Details
Main Author: Wu, Xiao
Other Authors: O'Brien, Peter
Published: University of York 2013
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581669