Comparisons of solution structures of free and IL-1β bound Fab suggests a model for B cell receptor signalling

Therapeutic antibodies are an important and growing class of biotherapeutics with the potential to treat a range of major human diseases. Structural knowledge of the complexes formed between antibodies and target proteins would provide valuable information about the mode of action of the therapeutic...

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Bibliographic Details
Main Author: Hall, Catherine Jane
Other Authors: Carr, Mark
Published: University of Leicester 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579181