Catalytic and non-catalytic mechanisms involved in glutathione S-transferase Pi mediated cytoprotection

Glutathione S-transferases (GSTs) are a multi-gene family of enzymes involved in the detoxification of a wide range of electrophilic compounds and are an integral component to antioxidant defence in the mammalian cell. Among GST, the Pi class (GSTP1) is the most prominent extrahepatic isoform in hum...

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Bibliographic Details
Main Author: McGarry, David
Other Authors: Henderson, Colin ; Wolf, C
Published: University of Dundee 2012
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578887