PMS2 and its role in mismatch repair deficiency syndrome
The PMS2 protein IS a component of the post-replicative DNA mismatch repair (MMR) system, which acts to correct mispaired nucleotides and small insertion-deletion loops in new DNA duplexes. Biallelic mutations in any of several MMR genes result in a deficiency syndrome (MMR-D) that predisposes to ch...
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University of Leeds
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578642 |