Immune mediated and direct killing of colorectal cancer by reovirus

Colorectal cancer remains the second most prevalent cancer in the world. Novel treatment strategies are necessary, especially for the treatment of metastatic disease. Reovirus is a naturally occurring oncolytic virus which acts by both direct and immune-mediated mechanisms. Having shown promise in e...

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Bibliographic Details
Main Author: Adair, Robert Allan
Published: University of Leeds 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577369