Do miRNAs play a role in androgen-induced phenotypic expression in prostate epithelial cells?
Activation of the androgen receptor (AR) results in a phenotypic change in androgen-responsive cells; for example, in the human prostate carcinoma cell line LNCaP, androgens mediate proliferation. MicroRNAs (miRNA) are a class of short non-coding RNA that act as post-transcriptional regulators of ge...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576047 |