New approaches for the stereoselective synthesis of N-heterocycles

A stereoselective approach has been developed for the flexible synthesis of substituted 2-pyrrolidones and 2-piperidones. By employing the key Overman rearrangement, efficient transfer of stereochemistry was achieved, and an acylation and ring closing metathesis strategy afforded a library of target...

Full description

Bibliographic Details
Main Author: Daly, Mark
Published: University of Glasgow 2012
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.573828