Study of the key determinants of statistical power in large scale genetic association studies

A large number of participants is often required by association studies investigating the causal mechanisms of complex diseases because of the generally weak causal effects involved in these conditions. The large sample sizes necessary for adequately powered analyses are mainly achieved by large stu...

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Bibliographic Details
Main Author: Gaye, Amadou
Other Authors: Burton, Paul R.; Tobin, Martin D.
Published: University of Leicester 2013
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572573