Statistical HLA type imputation from large and heterogeneous datasets

An individual's Human Leukocyte Antigen (HLA) type is an essential immunogenetic parameter, influencing susceptibility to a variety of autoimmune and infectious diseases, to certain types of cancer and the likelihood of adverse drug reactions. I present and evaluate two models for the accurate...

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Bibliographic Details
Main Author: Dilthey, Alexander Tilo
Other Authors: McVean, Gil
Published: University of Oxford 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572468

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