Statistical HLA type imputation from large and heterogeneous datasets
An individual's Human Leukocyte Antigen (HLA) type is an essential immunogenetic parameter, influencing susceptibility to a variety of autoimmune and infectious diseases, to certain types of cancer and the likelihood of adverse drug reactions. I present and evaluate two models for the accurate...
Main Author: | Dilthey, Alexander Tilo |
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Other Authors: | McVean, Gil |
Published: |
University of Oxford
2012
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572468 |
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