Pd-catalysed synthesis of functionalised adenosine analogues and their characterisation as base-discriminating fluorescent probes
A novel class of 7-modified 7-deazaadenosine nucleosides has been synthesised containing diarylacetylene groups at C7. Diarylacetylene boronate esters were synthesised by chemoselective Sonogashira cross-coupling. The boronate esters were then coupled to 7-iodo-7-deazaadenine nucleosides using aqueo...
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University of York
2012
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572363 |