Synthesis and ring-opening of NH-aziridine-2-carboxylates, and preparation of novel pyrazolo[3,4-d]pyrimidines for kinase-substrate identification

1: The ring-opening of aziridine-2-carboxylates dominates their reactivity, providing diverse, biologically relevant compounds. Less is known about the chemistry of NH-aziridine-2-carboxylates, owing to multi-step preparation, and lack of N-functionality to aid ring-opening. Building on the recent d...

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Bibliographic Details
Main Author: Ferguson, Alexandra
Other Authors: Armstrong, Alan
Published: Imperial College London 2013
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572245