Efficacy and mechanism of nicorandil in perioperative protection of skeletal muscle from ischaemia and reperfusion injury in a porcine model

Background: Prolonged ischaemia time during autogenous free muscle transfer, can lead to ischaemia reperfusion (I/R) injury and local necrosis of the muscle. It has been demonstrated that the phenomenon of ischaemic preconditioning (IPC) confers biphasic infarct protection in a porcine skeletal musc...

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Bibliographic Details
Main Author: Cahoon, Neil John
Published: University of Glasgow 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572151