The regulation of the cystic fibrosis transmembrane conductance regulator in human respiratory epithelia

Cystic fibrosis transmembrane conductance regulator (CFTR) is activated by cAMP-dependent phosphorylation, and functions as an ATP-dependent chloride channel involved predominantly in the movement of chloride ions to maintain cellular ionic homeostasis. Mutations in this channel cause cystic fibrosi...

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Bibliographic Details
Main Author: England, Alice
Other Authors: Robson, Louise ; Muimo, Richmond
Published: University of Sheffield 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.570166