Locating binding sites of the general anaesthetic propofol using photoaffinity labelling

3-(5’-isopropyl-6’-hydroxyphenyl)-3-trifluoromethyl-diazirine (photofol), a new drug developed in our laboratory, is structurally homologus to the general anaesthetic propofol with one of its isopropyl groups being substituted for a trifluoromethyl-diazirine group. Photofol was shown to act in a sim...

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Bibliographic Details
Main Author: Yip, Grace Mei Shan
Other Authors: Franks, Nick
Published: Imperial College London 2013
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.570074