Single-cell imaging and mathematical modelling of the hypoxia-inducible factor signalling network

Hypoxia-inducible Factor (HIF) is an oxygen-sensitive transcription factor present in all multicellular life, including humans. It is responsible for mediating the cellular response to hypoxia, a situation in which oxygen supply falls below adequate levels. In the presence of oxygen HIF is constitut...

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Bibliographic Details
Main Author: Bagnall, James Steven
Published: University of Liverpool 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569203