The role of base excision repair in regulating endotoxin induced inflammation

Endotoxins a component of the outer membrane of the cell wall of gram negative bacteria, stimulate the innate immune system to elicit an inflammatory response in mammals. Deletion of base excision repair (BER) genes has been reported to decrease the immune response to endotoxin in mouse models. It i...

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Bibliographic Details
Main Author: Carter, Alan Neil
Other Authors: Povey, Andrew; Elder, Rhoderick
Published: University of Manchester 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568615