α2-chimaerin and interacting proteins in axonal guidance signalling

Developing neurones require a dynamic cytoskeleton for newly forming processes to respond to guidance cues. The Rho GTPases, including Rac1, are very important in cytoskeleton remodelling. A GTPase activating protein (GAP) for Rac1, α2-chimaerin, participates in Semaphorin 3A (Sema 3A) and ephrin/Ep...

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Bibliographic Details
Main Author: Porchetta, C.
Published: University College London (University of London) 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568274