Longitudinal characterisation of neuropathology in transgenic and knock-in Huntington's disease mouse lines

The work presented in this thesis consists of 4 manuscripts, focussed on characterising the distribution of mutant huntingtin protein in transgenic and knock-in mouse models of Huntington’s disease. The mouse lines showed a different expression level of mutant huntingtin across the different time po...

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Bibliographic Details
Main Author: Bayram-Weston, Zubeyde
Published: Cardiff University 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567157