An investigation of the role of HIV-1 Gag mutation in failure of protease inhibitors
Classically, the emergence of resistance to protease inhibitors (PIs) in HIV-1 requires the stepwise accumulation of primary and compensatory mutations in the viral protease (PR). In addition, it was demonstrated that mutations occurring on one of the natural substrates of the PR, Gag, could behave...
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University College London (University of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565696 |