Preparation and characterization of engineered antigen presenting cells (APCs) for the generation of cytotoxic response for transplantation-related immunotherapy

Expansion and activation of cytotoxic T lymphocytes (CTL) is one of the major goals of immunotherapy but the hurdles in generating a large number of antigen-specific CTL are manifold. One of the limiting factors is the scarce availability of antigen presenting cell (APC) for T cell priming; dendriti...

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Bibliographic Details
Main Author: Zambetti, L. P.
Published: University College London (University of London) 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565615