Telomere length in cardiovascular disease and type 2 diabetes

Telomere attrition during mitosis is thought to be a mechanism for cell senescence, which is induced when the mean length reduces below a critical value. Oxidative DNA damage has been suggested to cause greater telomere loss per cell division. Thus telomere length indicates the cells' replicati...

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Bibliographic Details
Main Author: Salpea, K. K.
Published: University College London (University of London) 2011
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565544