Shh signalling and the dynamic patterning of the vertebrate neural tube

The formation of the central nervous system depends on the patterned generation of different neuronal and glial cell types during embryogenesis. In ventral regions of the neural tube, the graded activity of the secreted molecule Sonic Hedgehog (Shh) controls the position along the dorsoventral axis...

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Bibliographic Details
Main Author: Esteves Ribeiro, A. C.
Published: University College London (University of London) 2011
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565509