The role of immune inhibitory receptors in age-associated immune decline

The balance between signals delivered by positive and negative costimulatory molecules is crucial to the ultimate fate of cellular immune responses. Manipulation of T cell costimulatory pathways may offer a novel approach for reinvigorating exhausted T cell responses, especially in the context of ch...

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Bibliographic Details
Main Author: Macaulay, R.
Published: University College London (University of London) 2011
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565325