Lipid foulant interactions during the chromatographic purification of virus-like particles from Saccharomyces cerevisiae

The objective of this study was to understand the mechanism of lipid fouling in chromatography through the investigation of a hydrophobic interaction chromatography (HIC) operation. This was motivated by the need to understand this phenomenon during the manufacture of biological products such as vac...

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Bibliographic Details
Main Author: Jin, J.
Published: University College London (University of London) 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.565199